2006 List of rail accidents world wide:
- January 23, 2006 – Bioce train disaster: A passenger train crashes into a ravine near Podgorica, killing 46 and injuring 198.
- February 16, 2006 – Serres, Greece: An inter-city train strikes a truck at a grade crossing near Serres and derails. A passenger and the truck driver are killed, and twenty others on board the train are injured.
- March 13, 2006 – Austin, Texas, United States: Tara Rose McAvoy, 18, the reigning Miss Deaf Texas, is killed by the snowplow on a 65-car Union Pacific freight train while trespassing on the tracks and text-messaging her parents. The train sounded its horn repeatedly and attempted to apply the emergency brakes but could not stop before hitting McAvoy.
- April 5, 2006 – Indian Orchard, Massachusetts, United States: Patrick Deans, 18, High School football player struck and killed by CSX freight train while trespassing on the tracks. 2 CSX trains were traveling at once. Patrick was able to escape being struck by one, but was struck by the other.
- April 15, 2006 – Gubuck, Java: Thirteen die and 26 are injured as two trains collide and wreckage falls into a paddy field. One Swiss man was among the injured. Human error by the driver was officially blamed for the crash.
- April 28, 2006 – Victoria, Australia: A V/Line VLocity high-speed train is derailed when struck by an 18 wheeler truck, killing two and injuring 28 on the Ballarat to Ararat line.
- June 12, 2006 – Netanya, Israel: A passenger train from Tel Aviv to Haifa derails after colliding with a lorry on a level crossing, killing five and injuring more than 100.
- July 3, 2006 – Valencia metro accident in Valencia, Spain: A Valencia Metro train derails after leaving Jesús station, killing 41 and injuring at least 47. The records of the train's black box show that the train passed a bend where the speed is limited to 40 km/h at 80 km/h.
- July 11, 2006 – A series of bomb attacks strikes commuter trains in Mumbai, India, killing at least 200.
- July 14, 2006 – Luxembourg: A man sets a newspaper alight on board a train, resulting in a fire that injures 31, with seven people suffering critical injuries. The culprit is suspected to have a mental disorder.
- August 21, 2006 – Egypt: Two trains collide in the town of Qalyoub, 12 miles (20 kilometers) north of Cairo, killing 57 people and injuring 128.
- August 21, 2006 – Spain: A speeding eastbound RENFE intercity train derails in Villada, 40 km west of Palencia, leaving six people dead and 36 injured.
- August 27, 2006 – Zimbabwe: Five people are killed in a head-on collision between a passenger train and a freight train 30 km south of Victoria Falls.
- September 4, 2006 – Egypt: A passenger train collides with a freight train north of Cairo, killing five and injuring 30.
- September 22 2006 – Lathen, Emsland, Germany: 21 passengers and two maintenance workers die and many more are injured when a German Transrapid train collides with a maintenance of way vehicle on the system's test track near the Netherlands border.
- October 11, 2006 – 2006 Zoufftgen rail crash, near Metz, France: Passenger and freight service collide head on at Zoufftgen, Moselle, close to the Luxembourgish border. 5 people, including the drivers of both trains, are killed and 20 more are injured in the accident.. The accident is ascribed to human error in the controlling signalling centre in Luxembourg.
- October 17, 2006 – Rome Metro collision, Italy: Two metro trains collide at Rome's Vittorio Emanuele metro station, killing at least one person and injuring around 60 people.
- October 20, 2006 – New Brighton, PA - A train of tank cars containing ethanol derails on a bridge crossing the Beaver River. The resulting fire burns for days and forces some evacuations.
- November 9, 2006 – India- 40 dead and 15 injured in a West Bengal rail accident.
- November 13, 2006 – South Africa - A Metrorail train smashes into a truck carrying farm workers at a level crossing near Somerset West, killing 27 people.
- November 20, 2006 – India- A bomb explodes on a train near Belacoba station in West Bengal,